CAMAG - World Leader in Planar Chromatography
CAMAG Automatic Development Chamber 3 (ADC3)
The CAMAG Automatic Development Chamber 3 (ADC 3) continues the proven reliability of its predecessor in High-Performance Thin-Layer Chromatography (HPTLC), offering consistent, fully automated plate development to support reproducibility and data integrity.
Designed for 20 x 10 cm HPTLC plates, the ADC 3 features an integrated Twin Trough Chamber that ensures stable analytical conditions and minimizes variability. It offers full flexibility in solvent selection and development parameters, supporting a wide range of applications.
All critical steps – saturation, activation, pre-conditioning, development, and drying – are fully automated to eliminate environmental influences and deliver reproducible results. The built-in humidity control enables chromatography at defined layer activity, essential for robust method development and for evaluating humidity effects.
Seamless integration with visionCATS software ensures compliance with cGMP/GLP and 21 CFR Part 11, making the ADC 3 a reliable choice for regulated laboratories that demand precision, traceability, and efficiency.
Pre-Drying
Removes residual solvents before development
After sample application, the plate is subjected to a controlled pre-drying process. A built-in blower operates for a defined duration, eliminating any remaining solvent from the stationary phase, ensuring optimal conditions for reproducible results.
Chamber Saturation
Establishes a stable solvent environment
Before development, the twin-trough chamber is saturated with solvent vapours to create a consistent internal atmosphere. This ensures uniform distribution of vapors across the plate. A saturation pad further enhances vapor dispersion, contributing to reliable chromatographic behaviour.
Pre-Conditioning
Equilibrates the stationary phase
During pre-conditioning, the dry stationary phase is exposed to solvent vapors in a controlled environment. Solvent molecules present in the gas phase interact with the surface of the stationary phase, leading to modification of its properties.
Plate Activation
Humidity Control for Repeatable Performance
In most standardized methods, the plate is activated with air at a controlled relative humidity. Within a closed system, humidity is regulated using a saturated salt solution or molecular sieve.
Post-Development Drying
Prepares the plate for detection or evaluation
Once the development reaches the target migration distance, the plate is transferred to a drying unit. A controlled blower removes remaining mobile phase solvents, preparing the plate for the next analytical step.
Rinsing Procedure
Clean transition between solvent systems
When switching solvents, the system can be rinsed by adding solvent to the funnels. The glass tank can either be easily replaced with a clean one or cleaned and dried for reuse.
Ordering Information, Accessories and Parts
Part Number | Description |
|---|---|
ORL-022-8376 | Filter paper for chamber saturation ADC3, pack of 100 |
ORL-022-5262 | Twin trough chamber 20x10 cm for ADC 3 |
ORL-028-0000 | CAMAG® HPTLC Software visionCATS Basic Version Including access and control of all instruments - 1 server and 1 client, Instrument Diagnostics (xQ), Analytical reports - Access to method library. Needs to be purchased separately and is not included in any Ultimate Package. |
ORL-022-8600 | CAMAG® Automatic Developing Chamber 3 (ADC 3)
for fully automatic development of TLC/HPTLC plates of 20 x 10, including CAMAG Twin Through Chamber for ADC 3 (022.5262), for 20 x 10cm plates, 100 - 240 V
|
ORL-022-8373 | Foils clamping device for ADC 2 (from S/N 130601) |